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The risk of vitamin B12 deficiency is higher in patients with T2D receiving high metformin doses for an extended period or in the presence of other known risk factors associated with vitamin B12 deficiency, such as advanced age and regular use of acid-suppressing medications

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Furthermore, to clarify the role of L-carnitine in male fertility, in a randomized controlled trail in 2015, 20 couples with idiopathic oligoasthenozoospermia were admitted for treatment with L-carnitine (1000 mg/day ) for 3 to 6 months